SCHOTT Type I plus®

• The inside silicon dioxide coating of SCHOTT Type I plus® vials provides an effective barrier to ion leaching (sodium, calcium, boron, silicon and aluminum). 
• For production control, the standard Hydrolytic Resistance test is added by a special Type I plus® testing as a release criteria, SCHOTT specifies a limit value of 0.17 μg/ml Na after 6h autoclaving at 121 °C with 0.1 M HCl for all sizes.

• Tight geometric tolerances thanks to 100% camera inspection of dimensional and cosmetic parameters along the process line.
• Strict AQLs, with cosmetic defects a key part of the product specification. Any containers with critical defects are classified as "not allowed in the lot". 

• Enzymes and sensitive formulations
  Since no metal ions can be leached from the glass, the reactivity of enzymes and sensitive formulations is unaffected. 
   
• Radioactive diagnostics
  Less adsorption of radioactive molecules results in a reduction of residual radioactivity. 
   
• Proteins 
  The inner silicon dioxide coating of SCHOTT Type I plus® vials results in reduced adsorption of proteins. 
   
• Pure substances
  As the silicon dioxide coating is chemically inert, highly pure substances are preserved over long stocking periods. 
   
• WFI and alkali-sensitive products
  Unbuffered reagents such as water for injection are better protected against pH shifts.

• Increased shelf-life stability for sensitive drug formulations
• Minimized adsorption of proteins in liquid formulations – also prior to lyophilization
• Minimized adsorption of radioactive molecules